Eliminate Trigger Foods. Day 1 I felt no difference. Therefore, I cut the pills in half (2.5mg) and toss the other half. Traish AM, Melcangi RC, Bortolato M, Garcia-Segura LM, Zitzmann M. Rev Endocr Metab Disord. I do not think we have an answer to that question one way or the other. For details, see text., Side effects of treatment with 5 alpha-reductase inhibitors in experimental models. Ive read theres on guy there who recoverd recently from HCG, very interesting. I haven't had that sort of performance since I was 19 or 20 years old. 2022 Jul 27;15(8):930. doi: 10.3390/ph15080930. However, some men report persistent sex drive and ejaculation problems after stopping the medication. If you have retrograde ejaculation, you'll likely need treatment to get your female partner pregnant. Treatment for Post Finasteride Syndrome There is no known treatment of PFS. ._2a172ppKObqWfRHr8eWBKV{-ms-flex-negative:0;flex-shrink:0;margin-right:8px}._39-woRduNuowN7G4JTW4I8{margin-top:12px}._136QdRzXkGKNtSQ-h1fUru{display:-ms-flexbox;display:flex;margin:8px 0;width:100%}.r51dfG6q3N-4exmkjHQg_{font-size:10px;font-weight:700;letter-spacing:.5px;line-height:12px;text-transform:uppercase;-ms-flex-pack:justify;justify-content:space-between;-ms-flex-align:center;align-items:center}.r51dfG6q3N-4exmkjHQg_,._2BnLYNBALzjH6p_ollJ-RF{display:-ms-flexbox;display:flex}._2BnLYNBALzjH6p_ollJ-RF{margin-left:auto}._1-25VxiIsZFVU88qFh-T8p{padding:0}._2nxyf8XcTi2UZsUInEAcPs._2nxyf8XcTi2UZsUInEAcPs{color:var(--newCommunityTheme-widgetColors-sidebarWidgetTextColor)} I have had a recent report of a man who went on Human Growth Hormone and reversed his post finasteride syndrome sexual dysfunction. I did three months on testosterone injections and muscle building. Inability to concentrate. The problem is that most docs prescribe it at excessively high levels (5 mg/day). In addition, molecular mechanisms and/or genetic determinants behind such adverse effects have been poorly explored both in patients and animal models. J Sex Med. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). I tried proviron for a short time but it made me feel worse. At first, I felt absolutely miserable when doing so, it is the worst Ive felt in my life and I was unable to do almost anything but after some weeks it became more tolerable as the receptors lost some of their sensitivity. doi: 10.1177/0960327119842195. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. Here's some information to help you get ready for your appointment, and what to expect from your doctor. Im on HCG now too though so who knows, maybe itll help too, Powered by Discourse, best viewed with JavaScript enabled, Video: "Is Post Finasteride Syndrome Real? Mods are always talking about the survey too, I said a survey wont cure us and we could be be waiting for 10 years if we dont do anything. Unauthorized use of these marks is strictly prohibited. I remember being depressed, emasculated, and hopeless. When dosed properly, it can bring DHT within normal ranges very effectively. I have been prescribed a 2.5% DHT gel that is applied to the shoulders and forehead once a day. 2022 Apr;181:157-166. doi: 10.1016/j.brainresbull.2022.01.020. Is there a generic alternative to the medicine you're prescribing me? At some point you just cant store it all or want to use old drug. With prostate cancer deaths overtaking that of breast cancer, it is important to know the side effects of finasteride. If we cant discuss potential cures then that forum is completely worthless and I start to doubt their real intentions. This content does not have an English version. Ive been doing this for over 2 years and have ZERO sexual side effects from the drug. This condition, termed post-finasteride syndrome (PFS) is characterized by sexual side effects (i.e., low libido, erectile dysfunction, decreased arousal and difficulty in achieving orgasm), depression, anxiety and cognitive complaints that are still present despite drug withdrawal. ._3Z6MIaeww5ZxzFqWHAEUxa{margin-top:8px}._3Z6MIaeww5ZxzFqWHAEUxa ._3EpRuHW1VpLFcj-lugsvP_{color:inherit}._3Z6MIaeww5ZxzFqWHAEUxa svg._31U86fGhtxsxdGmOUf3KOM{color:inherit;fill:inherit;padding-right:8px}._3Z6MIaeww5ZxzFqWHAEUxa ._2mk9m3mkUAeEGtGQLNCVsJ{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;color:inherit} I did the first day 300 mg clomid, then 100mg for the first two weeks, 50mg for the third week, and none for the forth week. For details,, MeSH No energy. Minoxidil is FDA approved for genetic hair loss - it does not help other conditions quite so much. However, the side effects of a medication usually go away when you stop taking it. Finasteride causes cognitive & sexual decline. WebPost finasteride syndrome is real. -, Baig M.S., Kolasa-Wolosiuk A., Pilutin A., Safranow K., Baranowska-Bosiacka I., Kabat-Koperska J., Wiszniewska B. Finasteride-induced inhibition of 5alpha-reductase type 2 could lead to kidney damage-animal, experimental study. I took a prescription-strength anti-estrogen, Tamoxifen 10mg, twice a day: one at around 3pm and another one together with my test booster before bedtime. Have you been on hackstasis? Public Health. Now I can happily say that I no longer have any problem, strong erection all day and all night. When did you first begin having dry orgasms? Get the latest in health news delivered to your inbox! ._9ZuQyDXhFth1qKJF4KNm8{padding:12px 12px 40px}._2iNJX36LR2tMHx_unzEkVM,._1JmnMJclrTwTPpAip5U_Hm{font-size:16px;font-weight:500;line-height:20px;color:var(--newCommunityTheme-bodyText);margin-bottom:40px;padding-top:4px;text-align:left;margin-right:28px}._2iNJX36LR2tMHx_unzEkVM{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex}._2iNJX36LR2tMHx_unzEkVM ._24r4TaTKqNLBGA3VgswFrN{margin-left:6px}._306gA2lxjCHX44ssikUp3O{margin-bottom:32px}._1Omf6afKRpv3RKNCWjIyJ4{font-size:18px;font-weight:500;line-height:22px;border-bottom:2px solid var(--newCommunityTheme-line);color:var(--newCommunityTheme-bodyText);margin-bottom:8px;padding-bottom:8px}._2Ss7VGMX-UPKt9NhFRtgTz{margin-bottom:24px}._3vWu4F9B4X4Yc-Gm86-FMP{border-bottom:1px solid var(--newCommunityTheme-line);margin-bottom:8px;padding-bottom:2px}._3vWu4F9B4X4Yc-Gm86-FMP:last-of-type{border-bottom-width:0}._2qAEe8HGjtHsuKsHqNCa9u{font-size:14px;font-weight:500;line-height:18px;color:var(--newCommunityTheme-bodyText);padding-bottom:8px;padding-top:8px}.c5RWd-O3CYE-XSLdTyjtI{padding:8px 0}._3whORKuQps-WQpSceAyHuF{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px}._1Qk-ka6_CJz1fU3OUfeznu{margin-bottom:8px}._3ds8Wk2l32hr3hLddQshhG{font-weight:500}._1h0r6vtgOzgWtu-GNBO6Yb,._3ds8Wk2l32hr3hLddQshhG{font-size:12px;line-height:16px;color:var(--newCommunityTheme-actionIcon)}._1h0r6vtgOzgWtu-GNBO6Yb{font-weight:400}.horIoLCod23xkzt7MmTpC{font-size:12px;font-weight:400;line-height:16px;color:#ea0027}._33Iw1wpNZ-uhC05tWsB9xi{margin-top:24px}._2M7LQbQxH40ingJ9h9RslL{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px} Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. (photo). Around 8 months and i was pretty much recovered. ._3oeM4kc-2-4z-A0RTQLg0I{display:-ms-flexbox;display:flex;-ms-flex-pack:justify;justify-content:space-between} Urologic Clinics of North America. Took finasteride for 5 months. https://www.amazon.com/reviews/R3OGTPUQ1CP005. What's the best treatment to use to try to get my partner pregnant? Answer: Hormonal optimization while on finesteride there are many options including peptides, and HCG as well as clomid/arimidex. What was the article? So yes, it is not Dermatologic Surgeon, Board Certified in Dermatology, How Long Does Minoxidil 5 Take to Work? HHS Vulnerability Disclosure, Help I did this for 6 months straight but at the 10th week or so, the improvements were weekly. Firstly, hair loss doesn't just affect older people. As a service to our readers, Harvard Health Publishing provides access to our library of archived content. National Library of Medicine Resolve: The National Infertility Association. After 4 months of no progress whatsoever I tried the regimen that saved me - at least thats the only explanation I have. My doctor put me on 5mg daily cialis (+up to 15mg as needed before sex) clomiphene 25mg/daily anastrozole 1mg/week Addyi shockwave therapy ($3000 for 6 sessions) though this is definitely unnecessary and experimental. Disorders of male orgasm and ejaculation. I have not made any drastic life changes since beginning this. Now and for the past six months, I feel great, my libido is great, mental issues are gone, ED is gone. A. Finasteride (sold as Proscar and generic brands) is prescribed for symptoms of an enlarged prostate; it's also used at a lower strength (under the name Propecia) for male pattern baldness. Even Viagra wouldnt get me hard. 2016;93:9. Mehta A, et al. And yeah I know hackstasis, looks to be a much better community and forum than propeciahelp without fascist mods. I read the thing on Healthline where it says it doesn't raise testosterone in humans. I also started a thread but they merged it. Unable to load your collection due to an error, Unable to load your delegates due to an error. Key takeaways: Finasteride is an FDA-approved medication that treats hair loss in men. Sometimes, more-advanced assisted reproductive techniques are needed. Teeranachaideekul V, Parichatikanond W, Junyaprasert VB, Morakul B. The only thing that makes sense is to push your androgen receptors and epigenetics the opposite way fin did. ._12xlue8dQ1odPw1J81FIGQ{display:inline-block;vertical-align:middle} I tried just about everything over 11 years. Ask questions about your symptoms and how long you've had them. As a 5-alpha reductase inhibitor, finasteride works by inhibiting the effects of the enzyme thats responsible for converting testosterone into dihydrotestosterone (DHT). Why not save the other half for your next dose? Should I be concerned? Accessibility Stay on top of latest health news from Harvard Medical School. http://www.resolve.org/about-infertility/what-is-infertility/frequently-asked-questions-about-infertility.html. Hcg I did 3000iu the first day then 250iu every other day for the four weeks. @keyframes ibDwUVR1CAykturOgqOS5{0%{transform:rotate(0deg)}to{transform:rotate(1turn)}}._3LwT7hgGcSjmJ7ng7drAuq{--sizePx:0;font-size:4px;position:relative;text-indent:-9999em;border-radius:50%;border:4px solid var(--newCommunityTheme-bodyTextAlpha20);border-left-color:var(--newCommunityTheme-body);transform:translateZ(0);animation:ibDwUVR1CAykturOgqOS5 1.1s linear infinite}._3LwT7hgGcSjmJ7ng7drAuq,._3LwT7hgGcSjmJ7ng7drAuq:after{width:var(--sizePx);height:var(--sizePx)}._3LwT7hgGcSjmJ7ng7drAuq:after{border-radius:50%}._3LwT7hgGcSjmJ7ng7drAuq._2qr28EeyPvBWAsPKl-KuWN{margin:0 auto} .LalRrQILNjt65y-p-QlWH{fill:var(--newRedditTheme-actionIcon);height:18px;width:18px}.LalRrQILNjt65y-p-QlWH rect{stroke:var(--newRedditTheme-metaText)}._3J2-xIxxxP9ISzeLWCOUVc{height:18px}.FyLpt0kIWG1bTDWZ8HIL1{margin-top:4px}._2ntJEAiwKXBGvxrJiqxx_2,._1SqBC7PQ5dMOdF0MhPIkA8{vertical-align:middle}._1SqBC7PQ5dMOdF0MhPIkA8{-ms-flex-align:center;align-items:center;display:-ms-inline-flexbox;display:inline-flex;-ms-flex-direction:row;flex-direction:row;-ms-flex-pack:center;justify-content:center} Im suffering from pfs for 3+ years now so pfs is very real sadly but I believe the dudes article is the best explenation Ive read so far. government site. But it is a risk men should discuss with their doctor prior to starting finasteride. Best, Dr. Emer. 2020 Jan;113(1):21-50. doi: 10.1016/j.fertnstert.2019.11.030. Plentiful in opinions, short on facts. The common denominator in how I feel is Tribulus, period, end of sentence. BONUS! https://forum.propeciahelp.com/t/i-think-im-healed-after-six-year-nightmare/35477. Case report: a study of the clinical characteristics and genetic variants of post-finasteride syndrome patients. | How To Diagnose And Reverse It. The site is secure. The article stated proviron was the best potential cure in his opinion. Feeling low-grade depression constantly. Don't listen to bad doctors who tell you its all in your head. I took intramuscular injections of HCG every 3 a 5 days 1500 to 3000 ui by injections for 1 months only, and after that some Clomid for 10 days 2 pills by day It helped relaunch the natural testorene levels so my libido increased again i am now totally satisfied with my health :slight_smile: https://forum.propeciahelp.com/t/i-believe-i-have-been-cured-by-accident/4054, Yes After nearly 4 years of suffering, I have finally & fully recovered from Post Finasteride Syndrome, All my symptoms have subsided and improved with this method which takes a while but I am fully functional. Almost starting to think like a conspiracy theorist. In: Ferri's Clinical Advisor 2022. And quite frankly, if you think big pharma doesn't have millions and millions of dollars wrapped up in trying to cover up just how severely finasteride has destroyed mens' lives, you're fooling yourself. https://old.reddit.com/r/PostFinSyndrome/comments/ogcsjc/i_recovered_from_pfs_it_is_possible/. I guess that never happened. I suspect its because my E2 was so low already and that made it feel even lower (single digits if I recall correctly). On a sidenote i've seen a few other people recover the same way. Mod also deleted my second post where I said he indeed has affiliate links to herbs but doesnt even believe that will be enough for pfs patients, the real cure is proviron. 2023 by The President and Fellows of Harvard College, Do not sell my personal information | Privacy Policy. Preparing a list of questions before your appointment can help you make the most of your time together. 8600 Rockville Pike To be honest, I think for the most part these recoveries werent PFS but rather hormonal imbalances. Don't miss your FREE gift. 2016;101:46694680. Fertil Steril. -, Basaria S., Jasuja R., Huang G., Wharton W., Pan H., Pencina K., Li Z., Travison T.G., Bhawan J., Gonthier R., Labrie F., Dury A.Y., Serra C., Papazian A., O'Leary M., Amr S., Storer T.W., Stern E., Bhasin S. Characteristics of men who report persistent sexual symptoms after finasteride use for hair loss. You're right. Examples include bladder neck surgery and transurethral resection of the prostate. Would you like email updates of new search results? However, careful selection of patients and monitoring the finasteride treatment may prevent the PFS to some extent. AR: androgen receptor; CSF: cerebrospinal fluid; MRI: magnetic resonance imaging; SRD5A2: 5 alpha reductase type 2 gene. 2015;104:107. Before This is not proof that finasteride is to blame, since a variety of medical conditions and other prescription drugs could explain the sexual symptoms. I felt fine while taking it but it gave me gyno so I stopped. Sign up to get tips for living a healthy lifestyle, with ways to fight inflammation and improve cognitive health, plus the latest advances in preventative medicine, diet and exercise, pain relief, blood pressure and cholesterol management, andmore. I took a step back and said forget about PFS with these blood tests and these symptoms, whats the normal course of action? Metab. Not orgasm strength and sperm levels have returned, just waiting on my brain to communicate with my penis when its time for sexual intercourse. The results have been amazing and far too great to chalk it up to just being a placebo. .c_dVyWK3BXRxSN3ULLJ_t{border-radius:4px 4px 0 0;height:34px;left:0;position:absolute;right:0;top:0}._1OQL3FCA9BfgI57ghHHgV3{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex;-ms-flex-pack:start;justify-content:flex-start;margin-top:32px}._1OQL3FCA9BfgI57ghHHgV3 ._33jgwegeMTJ-FJaaHMeOjV{border-radius:9001px;height:32px;width:32px}._1OQL3FCA9BfgI57ghHHgV3 ._1wQQNkVR4qNpQCzA19X4B6{height:16px;margin-left:8px;width:200px}._39IvqNe6cqNVXcMFxFWFxx{display:-ms-flexbox;display:flex;margin:12px 0}._39IvqNe6cqNVXcMFxFWFxx ._29TSdL_ZMpyzfQ_bfdcBSc{-ms-flex:1;flex:1}._39IvqNe6cqNVXcMFxFWFxx .JEV9fXVlt_7DgH-zLepBH{height:18px;width:50px}._39IvqNe6cqNVXcMFxFWFxx ._3YCOmnWpGeRBW_Psd5WMPR{height:12px;margin-top:4px;width:60px}._2iO5zt81CSiYhWRF9WylyN{height:18px;margin-bottom:4px}._2iO5zt81CSiYhWRF9WylyN._2E9u5XvlGwlpnzki78vasG{width:230px}._2iO5zt81CSiYhWRF9WylyN.fDElwzn43eJToKzSCkejE{width:100%}._2iO5zt81CSiYhWRF9WylyN._2kNB7LAYYqYdyS85f8pqfi{width:250px}._2iO5zt81CSiYhWRF9WylyN._1XmngqAPKZO_1lDBwcQrR7{width:120px}._3XbVvl-zJDbcDeEdSgxV4_{border-radius:4px;height:32px;margin-top:16px;width:100%}._2hgXdc8jVQaXYAXvnqEyED{animation:_3XkHjK4wMgxtjzC1TvoXrb 1.5s ease infinite;background:linear-gradient(90deg,var(--newCommunityTheme-field),var(--newCommunityTheme-inactive),var(--newCommunityTheme-field));background-size:200%}._1KWSZXqSM_BLhBzkPyJFGR{background-color:var(--newCommunityTheme-widgetColors-sidebarWidgetBackgroundColor);border-radius:4px;padding:12px;position:relative;width:auto} Your doctor will ask you questions about your health and symptoms. Its like they want to hide possible solutions. https://forum.propeciahelp.com/t/cured-after-11-years/42363. Do you have cloudy urine after an orgasm? This procedure is usually done at the doctor's office. Indian J Plast Surg. Samplaski MK, et al. After numerous labs, I have determined that a dose of 2-3 mg is optimal for keeping my DHT within the normal range. The dosage needs to be low and steady, do not increase or add a day thinking more is better. After I got PFS my libido died, I stopped liking women, my brain wouldn't work, and my personality changed to a 90 old man. For what it's worth, here's a couple similar success stories involving numbness, but from PSSD instead of PFS: Testosterone along with initial estrogen management , completely cured my pssd, everything from numbness, to hard on quality , no morning wood, to actually having sexual desires again. The https:// ensures that you are connecting to the .ehsOqYO6dxn_Pf9Dzwu37{margin-top:0;overflow:visible}._2pFdCpgBihIaYh9DSMWBIu{height:24px}._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu{border-radius:2px}._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu:focus,._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu:hover{background-color:var(--newRedditTheme-navIconFaded10);outline:none}._38GxRFSqSC-Z2VLi5Xzkjy{color:var(--newCommunityTheme-actionIcon)}._2DO72U0b_6CUw3msKGrnnT{border-top:none;color:var(--newCommunityTheme-metaText);cursor:pointer;padding:8px 16px 8px 8px;text-transform:none}._2DO72U0b_6CUw3msKGrnnT:hover{background-color:#0079d3;border:none;color:var(--newCommunityTheme-body);fill:var(--newCommunityTheme-body)} Post-finasteride syndrome (PFS) is a constellation of serious adverse side effects manifested in clinical symptoms that develop and persist in patients during and/or after discontinuing finasteride treatment in men with pattern hair loss (androgenetic alopecia) or benign prostatic hyperplasia. I feel deeply for all my balding brothers out there who are suffering from this poison. Post-finasteride syndrome: a surmountable challenge for clinicians. WebPost-finasteride syndrome (PFS) is a constellation of serious adverse side effects manifested in clinical symptoms that develop and persist in patients during and/or after discontinuing finasteride treatment in men with pattern hair loss (androgenetic alopecia) or I read about the Post-Fin Syndrome and decided to quit (Almost) No erections, no libido. I suspect that 2 mg would be adequate, but if my doc prescribes two 1mg pills per day, the insurance company wont pay for it because the 1mg pill is only approved for hair loss treatment. Res. Minoxidil takes 4-6 months before an individual should assess whether or not it helps. Retrograde ejaculation can be especially challenging if you and your partner want to conceive a child. A single copy of these materials may be reprinted for noncommercial personal use only. My hair loss is back full force, but so is my libido and so are my erections. WebA deterioration in the quality of life in affected individuals does not justify use of the drug. These anecdotes report success using steroids or ancillaries. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA). If youre experiencing a medical issue, please contact a healthcare professional or dial 911 immediately. Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. Is my condition likely temporary or chronic? Very controversial topic in this forum. At higher doses, finasteride (Proscar) can also treat benign prostatic hyperplasia (BPH). This is a summary of the protocol which I followed for 6 months which eventually cured me. Andracim Gel (small 2 eminem size, 1 on each size of rib cage, less is more with this stuff). Yeah, that guy's comment history is really puzzling: When i dared visit PFS forums, the most miserable users there were still in a better state than me. I had all the classic symptoms. Or at the very least allow people to post ideas. Tamoxifen I did 20mg during the four weeks every day. .s5ap8yh1b4ZfwxvHizW3f{color:var(--newCommunityTheme-metaText);padding-top:5px}.s5ap8yh1b4ZfwxvHizW3f._19JhaP1slDQqu2XgT3vVS0{color:#ea0027} Jefferys A, et al. 12th ed. Any doctor interested in giving an opinion on the case? Its H.C.G (HCG) dosed at 250IU Monday, Wednesday and Friday only. The mods on that forum are fascists and dont allow the opinion and theory of other people. Bethesda, MD 20894, Web Policies Your doctor might also ask about any health problems, surgeries or cancers you've had and what medications you take. Careers. Were on our own to beat this, just wait is the worst solution to pfs there is. Make a list of all medications, vitamins and supplements that you're taking. Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats. "I had a case of PFS that was a severe as it gets. Press question mark to learn the rest of the keyboard shortcuts. Over time, several studies have demonstrated that finasteride is a safe and well-tolerated drug, with rare and reversible side effects such as reduced sexual libido and ejaculatory volume, most commonly observed when prescribed in